Uptake and Biological Effects of Perfluorooctane Sulfonate Exposure in the Adult Eastern Oyster Crassostrea virginica

Details

• Journal Title:
  Archives of Environmental Contamination and Toxicology
• Personal Author:
  Aquilina-Beck, Allisan A. ; Reiner, Jessica L. ; Chung, Katy W. ; DeLise, Meaghan J. ; Key, Peter B. ; DeLorenzo, Marie E.
• NOAA Program & Office:
  NOS (National Ocean Service) ; NCCOS (National Centers for Coastal Ocean Science)
• Description:
  Perfluorooctane sulfonate (PFOS) is a legacy contaminant that has been detected globally within the environment and throughout numerous species, including humans. Despite an international ban on its use, this unique contaminant continues to persist in organisms and their surroundings due to PFOS’s inability to breakdown into nontoxic forms resulting in bioaccumulation. In this study, we analyzed the effects of a technical mixture of PFOS (linear and branched isomers) in the adult Eastern oyster, Crassostrea virginica, at 2 days and 7 days exposure. Biomarker analysis (lysosomal destabilization, lipid peroxidation, and glutathione assays) in oyster tissue along with chemical analysis (liquid chromatography tandem mass spectrometry) of PFOS in oyster tissue and water samples revealed the oysters’ ability to overcome exposures without significant damage to lipid membranes or the glutathione phase II enzyme system; however, significant cellular lysosomal damage was observed. The oysters were able to eliminate up to 96% of PFOS at 0.3 mg/L and 3 mg/L exposures when allowed to depurate for 2 days in clean seawater. Chemical analysis showed the linear isomer to be the prevailing fraction of the residual PFOS contained in oyster tissue. Results provide insight into possible detrimental cellular effects of PFOS exposure in addition to offering insight into contaminant persistence in oyster tissue.
• Keywords:
  American Oyster Toxicology American Oyster Eastern oyster
• Source:
  Archives of Environmental Contamination and Toxicology, 79(3), 333-342
• DOI:
  https://doi.org/10.1007/s00244-020-00765-4
• Format:
  PDF
• Document Type:
  Journal Article
• Rights Information:
  Accepted Manuscript
• Rights Statement:
  The NOAA IR provides access to this content under the authority of the government's retained license to distribute publications and data resulting from federal funding. While users may legally access this content, the copyright owners retain rights that govern the reproduction, redistribution, and re-use of this work. The user is solely responsible for complying with applicable copyright law.
• Compliance:
  Submitted
• Main Document Checksum:
  urn:sha-512:70afa4b0e5cf7f56ed22e6a3f8ed2cf8109ca8dc74543ac3d22cfac6f065c73368b3fb265c633edb00e6d370c987ff0ea605e26a72bcafacc8de9d27065c7e2f
• Download URL:
  https://repository.library.noaa.gov/view/noaa/55919/noaa_55919_DS1.pdf
• File Type:
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