Details:

Journal Title:
Community Dentistry and Oral Epidemiology
Personal Author:
Golding, Jean ; Steer, Colin D. ; Gregory, Steven ; Lowery, Tony ; Hibbeln, Joseph R. ; ... More +
Golding, Jean ; Steer, Colin D. ; Gregory, Steven ; Lowery, Tony ; Hibbeln, Joseph R. ; Taylor, Caroline M. Less -
NOAA Program & Office:
NMFS (National Marine Fisheries Service)
Description:
Objectives: There is curiosity concerning the source of mercury that is absorbed into the mother's blood and which may affect the developing fetus. This study therefore sets out to determine the extent to which dental amalgam (DA) may contribute to total blood mercury (TBHg) levels of pregnant women in the UK.

Methods: Whole blood samples and information on diet and socio‐demographic factors were collected from pregnant women (n = 4484) enrolled in the Avon Longitudinal Study of Parents and Children (ALSPAC). The whole blood samples were assayed for total mercury levels using inductively coupled plasma dynamic reaction cell mass spectrometry (ICP‐DRC‐MS), and the women were retrospectively asked about features of their dental care during the pregnancy. Linear regression was used to estimate the relative contributions of DA to TBHg levels (log‐transformed) based on R 2 values, compared to the results from dietary and socio‐demographic variables.

Results: The contribution to the variance of the mothers' TBHg levels by dental variables was 6.47%, a figure comparable to the 8.75% shown for seafood consumption in this population. Dietary and dental variables explained 20.16% of the variance, with socio‐demographic variables contributing only a further 3.40%. The number of amalgams in the mouth at the start of pregnancy accounted for most of the variance in dental variables.


Keywords:
[+]
Mercury Toxicology
Source:
Community Dent Oral Epidemiol. 2016 Jun; 44(3): 216–222.
DOI:
http://dx.doi.org/10.1111/cdoe.12208
Pubmed ID:
26688340
Pubmed Central ID:
PMC4840325
Document Type:
Journal Article
Rights Information:
CC BY
Compliance:
PMC
Main Document Checksum:
[+]
urn:sha256:4a0937a0ff70d86c1fbadc425830d6e2310fc23d163c4854bbb8385cbc9eccb3
Download URL:
https://repository.library.noaa.gov/view/noaa/26302/noaa_26302_DS1.pdf
File Type:

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