Occurrence, endocrine-related bioeffects and fate of bisphenol A chemical degradation intermediates and impurities: A review

Pahigian, Jamie M.; Zuo, Yuegang

doi:10.1016/j.chemosphere.2018.05.117

i

Occurrence, endocrine-related bioeffects and fate of bisphenol A chemical degradation intermediates and impurities: A review

2018
By Pahigian, Jamie M. ; Zuo, Yuegang

Details

Journal Title:

Chemosphere
Personal Author:

Pahigian, Jamie M. ; Zuo, Yuegang
NOAA Program & Office:

NOAA General Documents
Description:

In recent decades, increasing attention has been directed toward the effects of bisphenol A (BPA) as an environmental pollutant, primarily due to its demonstrated endocrine-disruptive effects. A growing body of evidence indicates that many BPA derivatives also exhibit endocrine activity and other adverse biological properties. A review of the published literature was performed to identify BPA degradation intermediates resulting from chemical degradation processes of BPA, as well as BPA's associated co-pollutants. Products of biological metabolism were not included in this study. Seventy-nine chemicals were identified. Of these chemicals, a subset - those containing two 6-membered aromatic rings connected by a central ring-linking carbon - was identified, and a further literature review was conducted to identify demonstrated biological effects associated with the chemicals in this subset. The objectives of this review were to assess the potential risks to human and environmental health associated with BPA derivatives, characterize our current understanding of BPA's degradation intermediates and co-pollutants, and aid in the identification of compounds of interest that have received insufficient scrutiny.
Keywords:

Environmental Chemistry Environmental Engineering General Chemistry General Medicine Health, Toxicology And Mutagenesis Pollution Public Health, Environmental And Occupational Health Health, Toxicology And Mutagenesis Public Health, Environmental And Occupational Health Health, Toxicology And Mutagenesis
Source:

Chemosphere, 207, 469-480
DOI:

https://doi.org/10.1016/j.chemosphere.2018.05.117
ISSN:

0045-6535
Format:

PDF
Publisher:

Elsevier BV
Document Type:

Journal Article
Rights Information:

Accepted Manuscript
Compliance:

Library
Main Document Checksum:

urn:sha256:56e2055798b3d607403440491bb6167aba0f55b2af2f0e6da3afbed7f2850642
Download URL:

https://repository.library.noaa.gov/view/noaa/57593/noaa_57593_DS1.pdf
File Type:

[PDF - 1.36 MB ]

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