Subconjunctival antimicrobial poloxamer gel for treatment of corneal ulceration in stranded California sea lions (Zalophus californianus)

Simeone, Claire A.; Colitz, Carmen M. H.; Colegrove, Kathleen M.; Field, Cara L.; Rios, Carlos; Chandler, Heather L.; Johnson, Shawn P.

doi:10.1111/vop.12447

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Subconjunctival antimicrobial poloxamer gel for treatment of corneal ulceration in stranded California sea lions (Zalophus californianus)

2016
By Simeone, Claire A. ; Colitz, Carmen M. H. ; Colegrove, Kathleen M. ; ...
Source: Veterinary Ophthalmology, 20(5), 441-449

[PDF-340.36 KB]

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Journal Title:

Veterinary Ophthalmology
Personal Author:

Simeone, Claire A. ; Colitz, Carmen M. H. ; Colegrove, Kathleen M. ; Field, Cara L. ; Rios, Carlos ; ... More +

Simeone, Claire A. ; Colitz, Carmen M. H. ; Colegrove, Kathleen M. ; Field, Cara L. ; Rios, Carlos ; Chandler, Heather L. ; Johnson, Shawn P. Less -
NOAA Program & Office:

NMFS (National Marine Fisheries Service) ; OPR (Office of Protected Resources)

NMFS (National Marine Fisheries Service) ; OPR (Office of Protected Resources) Less -
Description:

Corneal ulcers are commonly encountered in pinnipeds. Prolonged oral antibiotics and topical ophthalmic solutions may not be practical to administer, and novel treatment techniques are desired. Thermodynamic gels are a potential solution because they hold antimicrobials at the site of injection, slowly releasing drug. This study investigated the clinical efficacy of antibiotic-impregnated poloxamer gel in management of corneal ulceration.
Keywords:

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General Veterinary
Source:

Veterinary Ophthalmology, 20(5), 441-449
DOI:

https://doi.org/10.1111/vop.12447
ISSN:

1463-5216;1463-5224;
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PDF
Publisher:

Wiley
Document Type:

Journal Article
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Accepted Manuscript
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Main Document Checksum:

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urn:sha256:b3148f242bfb065d8999a767f8ef090eb605c928249e0ac7926fdd4cf01bb1e8
Download URL:

https://repository.library.noaa.gov/view/noaa/56919/noaa_56919_DS1.pdf
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Subconjunctival antimicrobial poloxamer gel for treatment of corneal ulceration in stranded California sea lions (Zalophus californianus)

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