The NOAA IR serves as an archival repository of NOAA-published products including scientific findings, journal articles, guidelines, recommendations, or other information authored or co-authored by NOAA or funded partners.
As a repository, the NOAA IR retains documents in their original published format to ensure public access to scientific information.
i
Sex May Influence Environmental Diphenhydramine Accumulation In Round Stingrays
-
2018
-
Source: Marine Pollution Bulletin 135: 648-653
[PDF-528.37 KB]
Details:
-
Journal Title:Marine Pollution Bulletin
-
Personal Author:
-
NOAA Program & Office:
-
Sea Grant Program:
-
Description:Despite the amount of treated wastewater discharged into the Southern California Bight, few studies have examined pharmaceutical compounds in local biota. The Round Stingray (Urobatis halleri) was selected as a representative elasmobranch species to perform an exploratory study on environmental pharmaceutical exposure. Archived liver samples of males and females from juvenile to adult size classes from several locations (n = 53) were examined for 18 pharmaceutical and illicit drug compounds using isotope-dilution LC-MS/MS. Very few compounds were detected in stingray livers, with diphenhydramine as the only pharmaceutical above quantitation limits. Only stingrays collected from the urban site (mainland California) had detectable levels of diphenhydramine compared to no detections in reference stingrays (offshore island). Sex and sampling location substantially influenced both detection rate and concentrations. Our results suggest that aspects of species' ecology and physiology should be considered for future studies investigating pharmaceutical exposure in elasmobranchs.
-
Keywords:
-
Source:Marine Pollution Bulletin 135: 648-653
-
DOI:
-
Document Type:
-
Funding:
-
Place as Subject:
-
Rights Information:Accepted Manuscript
-
Compliance:Library
-
Main Document Checksum:
-
Download URL:
-
File Type:
